Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 8/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15345576 | 1.00 | CYP1A2 (0.41) | CYP1A2POLBCYP3A4CYP2C19RIPK1 | |
| SCHEMBL5152621 | 1.00 | CYP1A2 (0.41) | CYP1A2POLBCYP3A4CYP2C19RIPK1 | |
| SCHEMBL5152627 | 1.00 | CYP1A2 (0.41) | CYP1A2POLBCYP3A4CYP2C19RIPK1 | |
| SCHEMBL28396275 | 1.00 | CYP1A2 (0.41) | CYP1A2POLBCYP3A4CYP2C19RIPK1 | |
| SCHEMBL5150301 | 1.00 | CYP1A2 (0.41) | CYP1A2POLBCYP3A4CYP2C19RIPK1 | |
| SCHEMBL30743026 | 0.90 | CYP1A2 (0.37) | CYP1A2POLBCYP3A4CYP2C19SRC | |
| SCHEMBL5151940 | 0.90 | SRC (0.40) | CYP1A2POLBCYP3A4CYP2C19SRC | |
| SCHEMBL31122923 | 0.90 | CYP1A2 (0.37) | CYP1A2POLBCYP3A4CYP2C19SRC | |
| SCHEMBL5152054 | 0.90 | SRC (0.40) | CYP1A2POLBCYP3A4CYP2C19SRC | |
| SCHEMBL6543144 | 0.90 | SRC (0.40) | CYP1A2POLBCYP3A4CYP2C19SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813298-A | Imidazole indazole compounds as JAK inhibitors | 施万生物制药研发IP有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |