SCHEMBL29035844

SCHEMBL29035844

Fc1ccc(-c2n[nH]c(-c3ccccc3)n2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 7/20 0.79
NR1H3 Q13133 7/20 0.79
NPC1 O15118 4/20 0.70
RAB9A P51151 4/20 0.70
LMNA P02545 2/20 0.70
DGAT1 O75907 1/20 0.70
HPGDS O60760 1/20 0.65
SMN1; SMN2 Q16637 4/20 0.58
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
HPGD P15428 2/20 0.57
MAPT P10636 2/20 0.57
ALDH1A1 P00352 2/20 0.57
ATAD2 Q6PL18 1/20 0.57
TSHR P16473 1/20 0.57
HTT P42858 1/20 0.57
CYP1A2 P05177 2/20 0.54
TP53 P04637 1/20 0.54
ALPL P05186 1/20 0.54
CYP3A4 P08684 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15007066 0.93 NR1H2 (0.64) NR1H2NR1H3NPC1RAB9ALMNA
SCHEMBL26109969 0.91 NR1H2 (0.96) NR1H2NR1H3NPC1RAB9ALMNA
SCHEMBL17574086 0.91 NR1H2 (0.96) NR1H2NR1H3NPC1RAB9ALMNA
SCHEMBL17253717 0.89 NR1H2 (0.92) NR1H2NR1H3NPC1RAB9ALMNA
SCHEMBL17279700 0.89 NR1H2 (0.92) NR1H2NR1H3NPC1RAB9ALMNA
SCHEMBL666693 0.89 NR1H2 (1.00) NR1H2NR1H3NPC1RAB9ALMNA
SCHEMBL17280048 0.88 NPC1 (0.59) NR1H2NR1H3NPC1RAB9ALMNA
SCHEMBL1071190 0.87 NR1H2 (0.96) NR1H2NR1H3NPC1RAB9ALMNA
SCHEMBL17279695 0.82 NR1H2 (0.79) NR1H2NR1H3NPC1RAB9ALMNA
SCHEMBL29035842 0.82 NR1H2 (1.00) NR1H2NR1H3NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115532318-B MOF-supported metal catalyst and preparation method and application thereof 江南大学 2023-07-21 CN disclosed
CN-115532318-A MOF-loaded metal catalyst and preparation method and application thereof 江南大学 2022-12-30 CN disclosed