SCHEMBL29038792

SCHEMBL29038792

Nc1cncnc1.Nc1ncccn1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 6/20 0.60
CYP2A6 P11509 1/20 0.34
MAP4K4 O95819 1/20 0.34
HSP90AB1 P08238 2/20 0.34
PTK2 Q05397 1/20 0.34
EGFR P00533 2/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
PI4KA P42356 1/20 0.33
PI4K2B Q8TCG2 1/20 0.33
PI4K2A Q9BTU6 1/20 0.33
PI4KB Q9UBF8 1/20 0.33
GRM4 Q14833 3/20 0.33
ATM Q13315 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrimidine SCHEMBL21061720 0.81 HSP90AA1 (0.71) HSP90AA1CYP2A6HSP90AB1PTK2NOS3
Hydrochloric Acid SCHEMBL28134983 0.81
SCHEMBL97781 0.81
Hydrochloric Acid SCHEMBL6903913 0.78
Hydrochloric Acid SCHEMBL28125542 0.78
SCHEMBL25333076 0.78 HSP90AA1 (1.00) HSP90AA1MAP4K4HSP90AB1NOS3NOS1
SCHEMBL27136 0.78
Pyridine SCHEMBL27585289 0.77 TSHR (0.47) CYP2A6EGFRATMMEN1KMT2A
SCHEMBL1227188 0.74
Water SCHEMBL15769458 0.74 HSP90AA1 (0.92) HSP90AA1HSP90AB1NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116285777-A Self-repairing binder based on metal ion-polymer coordination bond and preparation method thereof 北京理工大学 2023-06-23 CN claimed
CN-116285777-A Self-repairing binder based on metal ion-polymer coordination bond and preparation method thereof 北京理工大学 2023-06-23 CN disclosed