Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 5/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL29064775 | 0.98 | EPHX2 (0.54) | EPHX2FAAHGPR84PPARGPPARD | |
| Acetic Acid SCHEMBL28884855 | 0.96 | EPHX2 (0.53) | EPHX2FAAHGPR84PPARGPPARD | |
| Acetic Acid SCHEMBL28884856 | 0.96 | EPHX2 (0.53) | EPHX2FAAHGPR84PPARGPPARD | |
| Acetic Acid SCHEMBL11049476 | 0.96 | EPHX2 (0.51) | EPHX2FAAHGPR84PPARGPPARD | |
| Acetone SCHEMBL27900517 | 0.91 | EPHX2 (0.56) | EPHX2FAAHCES2CES1 | |
| SCHEMBL61429 | 0.91 | EPHX2 (0.55) | EPHX2FAAHPPARACES2CES1 | |
| SCHEMBL37390 | 0.91 | EPHX2 (0.55) | EPHX2FAAHPPARACES2CES1 | |
| SCHEMBL5702178 | 0.91 | EPHX2 (0.55) | EPHX2FAAHPPARACES2CES1 | |
| SCHEMBL3859589 | 0.91 | EPHX2 (0.55) | EPHX2FAAHPPARACES2CES1 | |
| SCHEMBL5969692 | 0.91 | EPHX2 (0.55) | EPHX2FAAHPPARACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118190921-B | Acridine ester enhanced light-emitting system | 河北医陆生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-114206298-B | Stabilization of intermediate diphenol compounds in cosmetic compositions | 联合利华知识产权控股有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118190921-A | Acridine ester enhanced light-emitting system | 河北医陆生物科技有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-116234533-A | Compositions and methods for cleansing keratin materials | 欧莱雅 | 2023-06-06 | — | — | CN | disclosed |