Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 17/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17194889 | 0.81 | TYK2 (0.45) | TYK2JAK2JAK1KCNH2 | |
| SCHEMBL29039323 | 0.80 | TYK2 (0.44) | TYK2JAK2JAK1KCNH2 | |
| SCHEMBL15698670 | 0.79 | JAK2 (0.46) | TYK2JAK2JAK1KCNH2 | |
| SCHEMBL30702574 | 0.78 | TYK2 (0.45) | TYK2JAK2JAK1 | |
| SCHEMBL30468115 | 0.78 | TYK2 (0.46) | TYK2JAK2JAK1 | |
| SCHEMBL24288086 | 0.78 | TYK2 (0.45) | TYK2JAK2JAK1KCNH2 | |
| SCHEMBL15690539 | 0.78 | TYK2 (0.45) | TYK2JAK2JAK1 | |
| SCHEMBL20073648 | 0.78 | TYK2 (0.43) | TYK2JAK2JAK1KCNH2 | |
| SCHEMBL29020223 | 0.78 | TYK2 (0.46) | TYK2JAK2JAK1 | |
| SCHEMBL31369051 | 0.78 | TYK2 (0.47) | TYK2JAK2JAK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116262739-A | Nitrogen-containing aryl derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |