Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30506256 | 1.00 | RECQL (0.50) | RECQLSMN1; SMN2LMNAGAAPOLB | |
| SCHEMBL20116311 | 1.00 | RECQL (0.50) | RECQLSMN1; SMN2LMNAGAAPOLB | |
| SCHEMBL3181095 | 0.85 | MAPK1 (0.55) | RECQLSMN1; SMN2LMNAGAAPOLB | |
| SCHEMBL3181108 | 0.85 | MAPK1 (0.55) | RECQLSMN1; SMN2LMNAGAAPOLB | |
| SCHEMBL12402284 | 0.83 | POLB (0.49) | SMN1; SMN2LMNAGAAPOLBMEN1 | |
| SCHEMBL12574120 | 0.83 | POLB (0.49) | SMN1; SMN2LMNAGAAPOLBMEN1 | |
| SCHEMBL17730781 | 0.82 | RECQL (0.68) | RECQLSMN1; SMN2GAAPOLBMEN1 | |
| SCHEMBL17730782 | 0.82 | RECQL (0.68) | RECQLSMN1; SMN2GAAPOLBMEN1 | |
| SCHEMBL17737721 | 0.82 | RECQL (0.68) | RECQLSMN1; SMN2GAAPOLBMEN1 | |
| SCHEMBL20116382 | 0.81 | RECQL (0.50) | RECQLSMN1; SMN2LMNAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |