Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 5/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20117012 | 1.00 | RECQL (0.50) | RECQLPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3181108 | 0.85 | MAPK1 (0.55) | RECQLPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3181095 | 0.85 | MAPK1 (0.55) | RECQLPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17654454 | 0.84 | GAA (0.62) | RECQLRAB9AGAANPC1HSD17B10 | |
| SCHEMBL17654450 | 0.84 | GAA (0.62) | RECQLRAB9AGAANPC1HSD17B10 | |
| SCHEMBL20116518 | 0.84 | MAPK1 (0.44) | PDE4APDE4BPDE4CPDE4DRAB9A | |
| SCHEMBL2326648 | 0.82 | RECQL (0.68) | RECQLPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2326651 | 0.82 | RECQL (0.68) | RECQLPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20116382 | 0.81 | RECQL (0.50) | RECQLRAB9AGAAMAPK1NPC1 | |
| SCHEMBL30506256 | 0.81 | RECQL (0.50) | RECQLRAB9AGAANPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |