Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.48 |
| ▸ | CA2 | P00918 | 8/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28468535 | 1.00 | CA1 (0.48) | CA1CA2CA12CA9TDP1 | |
| SCHEMBL28899596 | 1.00 | CA1 (0.48) | CA1CA2CA12CA9TDP1 | |
| SCHEMBL29040477 | 1.00 | CA1 (0.48) | CA1CA2CA12CA9TDP1 | |
| SCHEMBL29040412 | 1.00 | CA1 (0.48) | CA1CA2CA12CA9TDP1 | |
| SCHEMBL597639 | 1.00 | CA1 (0.48) | CA1CA2CA12CA9TDP1 | |
| SCHEMBL28989021 | 0.99 | CA1 (0.47) | CA1CA2CA12CA9TDP1 | |
| SCHEMBL18544355 | 0.86 | CA12 (0.44) | CA1CA2CA12CA9TDP1 | |
| SCHEMBL25294572 | 0.85 | CA12 (0.43) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL21071014 | 0.85 | CA12 (0.43) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL12330710 | 0.82 | TDP1 (0.48) | CA1CA2CA12CA9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444494-A | Compound for targeted degradation of BUB1B and BUB1 protein, and preparation method and application thereof | 浙江大学 | 2023-07-18 | — | — | CN | disclosed |