SCHEMBL290428

SCHEMBL290428

Cc1nc(-c2cccnc2)sc1NC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.64
CYP1A2 P05177 4/20 0.64
CYP2C19 P33261 3/20 0.61
LMNA P02545 2/20 0.61
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
CYP2C9 P11712 2/20 0.57
CYP2D6 P10635 1/20 0.57
MAPT P10636 3/20 0.54
ALDH1A1 P00352 5/20 0.53
RAB9A P51151 1/20 0.53
KDM4E B2RXH2 5/20 0.50
GFER P55789 1/20 0.50
ALOX5 P09917 1/20 0.49
IRAK4 Q9NWZ3 2/20 0.47
HPGD P15428 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
CDC7 O00311 1/20 0.46
DBF4 Q9UBU7 1/20 0.46
CYP2E1 P05181 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13047816 0.90 CYP1A2 (0.62) CYP3A4CYP1A2CYP2C19LMNAMEN1
SCHEMBL13047855 0.88 CYP1A2 (0.60) CYP3A4CYP1A2CYP2C19LMNAMEN1
SCHEMBL13047554 0.87 CYP1A2 (0.58) CYP3A4CYP1A2CYP2C19LMNAMEN1
SCHEMBL13047865 0.86 CYP1A2 (0.57) CYP3A4CYP1A2CYP2C19LMNAMEN1
SCHEMBL16652459 0.85 CYP1A2 (0.53) CYP3A4CYP1A2CYP2C19LMNAMEN1
SCHEMBL12289747 0.84 CYP3A4 (0.60) CYP3A4CYP1A2CYP2C19LMNAMEN1
SCHEMBL18569129 0.84 CYP1A2 (0.55) CYP3A4CYP1A2CYP2C19LMNAMEN1
SCHEMBL13048454 0.84 CYP1A2 (0.55) CYP3A4CYP1A2CYP2C19LMNAMEN1
SCHEMBL290732 0.84 CYP1A2 (0.55) CYP3A4CYP1A2CYP2C19LMNAMEN1
SCHEMBL290778 0.84 CYP3A4 (0.59) CYP3A4CYP1A2CYP2C19LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105682462-A Pesticidal compositions and methods related thereto 美国陶氏益农公司 2016-06-15 CN disclosed
EP-2427191-A1 PESTICIDAL COMPOSITIONS Dow AgroSciences LLC (US) 2012-03-14 EP disclosed
WO-2010129497-A1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2010-11-11 WO disclosed