Malonic Acid

Malonic Acid

SCHEMBL29043333

NNc1nc2nccnc2c(=O)[nH]1.O=C(O)CC(=O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.40
KDM4E B2RXH2 1/20 0.40
AKR1B1 P15121 10/20 0.39
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPC1 O15118 1/20 0.33
ADORA2A P29274 1/20 0.33
GDA Q9Y2T3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycolic Acid SCHEMBL29043327 0.93 GAA (0.39) GAAKDM4EAKR1B1ALDH1A1HPGD
Acetic Acid SCHEMBL29043334 0.90 GAA (0.47) GAAKDM4EAKR1B1ALDH1A1HPGD
SCHEMBL1568354 0.89 GAA (0.40) GAAKDM4EAKR1B1ALDH1A1HPGD
SCHEMBL28068575 0.89 GAA (0.40) GAAKDM4EAKR1B1ALDH1A1HPGD
Hydrochloric Acid SCHEMBL28653465 0.88 GAA (0.39) GAAKDM4EAKR1B1ALDH1A1HPGD
SCHEMBL29972233 0.88 GAA (0.39) GAAKDM4EAKR1B1ALDH1A1HPGD
Ammonia Solution, Strong SCHEMBL28067449 0.88 GAA (0.39) GAAKDM4EAKR1B1ALDH1A1HPGD
Fumaric Acid SCHEMBL29043337 0.87 KDM4E (0.39) GAAKDM4EAKR1B1ALDH1A1HPGD
Methylene Chloride SCHEMBL27617307 0.87 GAA (0.37) GAAKDM4EAKR1B1ALDH1A1HPGD
Cadaverine Tartrate SCHEMBL29043324 0.86 GAA (0.39) GAAKDM4EAKR1B1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903624-B Polymorphs of aminopterin and salts thereof PTC medical MP Co. (US) 2026-05-26 CN disclosed
CN-116903624-A Polymorphs of aminopterin and salts thereof PTC医疗MP公司 2023-10-20 CN disclosed
CN-110248948-B Polymorphs of aminopterin and salts thereof PTC医疗MP公司 2023-07-28 CN disclosed