Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 6/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30758706 | 0.92 | TKT (0.51) | TKTHSP90AA1LMNADRD4 | |
| SCHEMBL261033 | 0.92 | TKT (0.51) | TKTHSP90AA1LMNADRD4 | |
| Hydrochloric Acid SCHEMBL1326627 | 0.91 | TKT (0.50) | TKTHSP90AA1LMNADRD4 | |
| Hydrochloric Acid SCHEMBL29404983 | 0.91 | TKT (0.50) | TKTHSP90AA1LMNADRD4 | |
| Hydrochloric Acid SCHEMBL9000282 | 0.90 | TKT (0.49) | TKTHSP90AA1LMNADRD4 | |
| Sulfuric Acid SCHEMBL27790987 | 0.87 | TKT (0.49) | TKTHSP90AA1LMNA | |
| Nitric Acid SCHEMBL27791065 | 0.85 | TKT (0.47) | TKTHSP90AA1LMNA | |
| Nitric Acid SCHEMBL27769557 | 0.85 | TKT (0.47) | TKTHSP90AA1LMNA | |
| SCHEMBL27941838 | 0.85 | TKT (0.41) | TKTHSP90AA1LMNADRD4 | |
| Hydrochloric Acid SCHEMBL16697601 | 0.84 | TKT (0.40) | TKTHSP90AA1LMNADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116531373-B | Thiazole compound, pharmaceutical composition and application thereof | 上海日馨医药科技股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-116531373-A | Thiazole compound, pharmaceutical composition and application thereof | 上海日馨医药科技股份有限公司 | 2023-08-04 | — | — | CN | disclosed |