Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 7/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29045330 | 0.84 | CA1 (0.46) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL6842368 | 0.82 | CYP1A2 (0.50) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL38665117 | 0.78 | CA1 (0.71) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL21729511 | 0.78 | CA1 (0.56) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL26405353 | 0.78 | CA1 (0.56) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL14098271 | 0.78 | CA1 (0.71) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL24669522 | 0.76 | CA1 (0.59) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL14980856 | 0.76 | CA1 (0.54) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL3389500 | 0.76 | CA1 (0.59) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL15081309 | 0.76 | CA1 (0.59) | CA1CA2CA7CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547287-A | Inhibitors of APOL1 and methods of use thereof | 弗特克斯药品有限公司 | 2023-08-04 | — | — | CN | disclosed |