SCHEMBL29045671

SCHEMBL29045671

CCOC(=O)C(C)=COc1ccc(C(C)(C)c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.45
ALDH1A1 P00352 9/20 0.45
MEN1 O00255 7/20 0.45
KMT2A Q03164 7/20 0.45
HTT P42858 2/20 0.45
POLB P06746 2/20 0.43
SMN1; SMN2 Q16637 5/20 0.41
GAA P10253 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
LMNA P02545 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPT P10636 2/20 0.40
HSP90AA1 P07900 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28446194 0.87 KDM4E (0.46) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL12851497 0.86 MEN1 (0.51) KDM4EALDH1A1MEN1KMT2APOLB
SCHEMBL93317 0.86 MEN1 (0.51) KDM4EALDH1A1MEN1KMT2APOLB
SCHEMBL13130215 0.83 MEN1 (0.46) KDM4EALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL12851380 0.83 NPC1 (0.51) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL12851379 0.83 MEN1 (0.46) KDM4EALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL13130217 0.83 NPC1 (0.51) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL12851453 0.80 DHODH (0.46) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6984038 0.79 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL11204204 0.79 AR (0.42) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115300400-A Transparent, fracture-tough polymeric resins for the production of dental molded bodies 义获嘉伟瓦登特公司 2022-11-08 CN claimed
CN-116940600-A Resin composition, cured product, laminate, transparent antenna, method for producing transparent antenna, and image display device 株式会社力森诺科 2023-10-24 CN disclosed
CN-115300400-A Transparent, fracture-tough polymeric resins for the production of dental molded bodies 义获嘉伟瓦登特公司 2022-11-08 CN disclosed