Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOXM1 | Q08050 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986120 | 0.89 | FOXM1 (0.66) | FOXM1KDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL29045797 | 0.89 | FOXM1 (0.66) | FOXM1KDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL29045851 | 0.85 | FOXM1 (0.77) | FOXM1KDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL29985891 | 0.82 | FOXM1 (0.73) | FOXM1KDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL29045850 | 0.82 | KDM4E (0.60) | FOXM1KDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL29045830 | 0.82 | FOXM1 (0.73) | FOXM1KDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL29045796 | 0.82 | FOXM1 (0.65) | FOXM1KDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL29045860 | 0.81 | FOXM1 (0.67) | FOXM1KDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL29045805 | 0.80 | FOXM1 (0.77) | FOXM1KDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL29045813 | 0.80 | FOXM1 (1.00) | FOXM1KDM4ESMN1; SMN2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304502-B | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-10-18 | — | — | CN | disclosed |
| CN-115304502-A | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2022-11-08 | — | — | CN | disclosed |