Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOXM1 | Q08050 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29045839 | 0.81 | FOXM1 (0.85) | FOXM1KDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL29045847 | 0.81 | FOXM1 (0.79) | FOXM1KDM4ESMN1; SMN2KMT2ARAB9A | |
| SCHEMBL3411535 | 0.80 | KMT2A (0.47) | FOXM1KDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL29045813 | 0.80 | FOXM1 (1.00) | FOXM1KDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL29045845 | 0.79 | FOXM1 (0.97) | FOXM1KDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL29045833 | 0.79 | FOXM1 (0.97) | FOXM1KDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL29045785 | 0.79 | FOXM1 (0.97) | FOXM1KDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL4480785 | 0.78 | EPHX2 (0.49) | FOXM1SMN1; SMN2KMT2ARAB9AALDH1A1 | |
| SCHEMBL29045834 | 0.78 | KDM4E (0.79) | FOXM1KDM4ESMN1; SMN2KMT2ARAB9A | |
| SCHEMBL321228 | 0.78 | FOXM1 (0.63) | FOXM1KDM4ESMN1; SMN2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304502-B | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-10-18 | — | — | CN | disclosed |
| CN-115304502-A | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2022-11-08 | — | — | CN | disclosed |