Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29045884 | 1.00 | KMT2A (0.68) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL30611213 | 1.00 | KMT2A (0.68) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL1171410 | 0.85 | KMT2A (0.69) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL1171415 | 0.85 | KMT2A (0.69) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL16968757 | 0.79 | KMT2A (0.58) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL15058588 | 0.79 | KMT2A (0.58) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL11465874 | 0.78 | KMT2A (0.56) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL6789997 | 0.78 | KMT2A (0.56) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL12905316 | 0.77 | KDM4E (0.67) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL22388821 | 0.77 | KDM4E (0.71) | KMT2AMEN1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304597-B | Beta-carboline compounds and application thereof in preparation of medicines for treating or preventing tumor diseases | 中国科学院深圳先进技术研究院 | 2023-10-20 | — | — | CN | disclosed |
| CN-115304597-A | Beta-carboline compounds and application thereof in preparing medicines for treating or preventing tumor diseases | 中国科学院深圳先进技术研究院 | 2022-11-08 | — | — | CN | disclosed |