Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 2/20 | 0.47 |
| ▸ | CHUK | O15111 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | C5 | P01031 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29045879 | 1.00 | PARP14 (0.47) | PARP14CHUKL3MBTL1PTGS2MAPT | |
| SCHEMBL29985536 | 1.00 | PARP14 (0.47) | PARP14CHUKL3MBTL1PTGS2MAPT | |
| SCHEMBL29045894 | 0.87 | HTR2C (0.44) | PARP14L3MBTL1DYRK1ABRAFNPC1 | |
| SCHEMBL29045901 | 0.87 | BCHE (0.49) | PARP14L3MBTL1MAPTDYRK1ABRAF | |
| SCHEMBL29045899 | 0.87 | BCHE (0.49) | PARP14L3MBTL1MAPTDYRK1ABRAF | |
| SCHEMBL29986612 | 0.87 | HTR2C (0.44) | PARP14L3MBTL1DYRK1ABRAFNPC1 | |
| SCHEMBL29986906 | 0.87 | BCHE (0.49) | PARP14L3MBTL1MAPTDYRK1ABRAF | |
| SCHEMBL29045890 | 0.87 | HTR2C (0.44) | PARP14L3MBTL1DYRK1ABRAFNPC1 | |
| SCHEMBL29986202 | 0.86 | AR (0.42) | PARP14CHUKL3MBTL1MEN1KMT2A | |
| SCHEMBL29045927 | 0.86 | JAK2 (0.44) | PARP14CHUKL3MBTL1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304597-B | Beta-carboline compounds and application thereof in preparation of medicines for treating or preventing tumor diseases | 中国科学院深圳先进技术研究院 | 2023-10-20 | — | — | CN | disclosed |
| CN-115304597-A | Beta-carboline compounds and application thereof in preparing medicines for treating or preventing tumor diseases | 中国科学院深圳先进技术研究院 | 2022-11-08 | — | — | CN | disclosed |