Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.53 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | MELK | Q14680 | 2/20 | 0.43 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546985 | 1.00 | RXFP1 (0.53) | RXFP1DAPK3PRKD3PIM1CDK2 | |
| SCHEMBL30546936 | 0.92 | RXFP1 (0.46) | RXFP1FLT3KMT2AMEN1 | |
| SCHEMBL29047707 | 0.92 | RXFP1 (0.46) | RXFP1FLT3KMT2AMEN1 | |
| SCHEMBL29047658 | 0.90 | RXFP1 (0.57) | RXFP1KMT2AMAPK14MAPTMEN1 | |
| SCHEMBL30546927 | 0.90 | RXFP1 (0.57) | RXFP1KMT2AMAPK14MAPTMEN1 | |
| SCHEMBL29047630 | 0.90 | RXFP1 (0.68) | RXFP1YAP1TEAD4TEAD2 | |
| SCHEMBL30546965 | 0.90 | RXFP1 (0.53) | RXFP1SLC10A2SLC10A1SLC10A6KMT2A | |
| SCHEMBL29047690 | 0.90 | RXFP1 (0.53) | RXFP1SLC10A2SLC10A1SLC10A6KMT2A | |
| SCHEMBL29047582 | 0.89 | RXFP1 (0.48) | RXFP1FLT3KMT2AAURKAAURKB | |
| SCHEMBL30546978 | 0.89 | RXFP1 (0.48) | RXFP1FLT3KMT2AAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535357-A | Arylamino benzamide derivative containing substituted pyrazole structure, preparation method and application | 西北农林科技大学 | 2023-08-04 | — | — | CN | disclosed |