SCHEMBL29048402

SCHEMBL29048402

CC(C)(C)OC(=O)Oc1ccc(B2OC(C)(C)C(C)(C)O2)cc1Br

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 2/20 0.45
BACE1 P56817 1/20 0.43
BACE2 Q9Y5Z0 1/20 0.43
PRMT5 O14744 1/20 0.41
WDR77 Q9BQA1 1/20 0.41
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
HIF1A Q16665 2/20 0.37
DGAT1 O75907 1/20 0.37
USP30 Q70CQ3 2/20 0.36
F2 P00734 1/20 0.35
F11 P03951 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
ROCK1 Q13464 1/20 0.35
ELANE P08246 1/20 0.35
LIPG Q9Y5X9 2/20 0.33
P4HB P07237 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29048403 0.85 AAK1 (0.58) AAK1BACE1BACE2PRMT5WDR77
SCHEMBL23258500 0.82 AAK1 (0.46) AAK1BACE1BACE2PRMT5WDR77
SCHEMBL16426109 0.80 PRMT5 (0.43) AAK1BACE1BACE2PRMT5WDR77
SCHEMBL23258496 0.79 PRMT5 (0.41) AAK1BACE1BACE2PRMT5WDR77
SCHEMBL29203706 0.79 AAK1 (0.49) AAK1BACE1BACE2PRMT5WDR77
SCHEMBL30298922 0.79 AAK1 (0.43) AAK1BACE1BACE2PRMT5WDR77
SCHEMBL2762706 0.79 ELANE (0.54) AAK1BACE1BACE2PRMT5WDR77
SCHEMBL1318656 0.77 ELANE (0.42) AAK1BACE1BACE2PRMT5WDR77
SCHEMBL1643646 0.76 HIF1A (0.42) AAK1BACE1BACE2PRMT5WDR77
SCHEMBL16687457 0.74 ELANE (0.38) AAK1BACE1BACE2PRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396316-B Preparation method of 3-methylbenzo [ d ] oxazole-2 (3H) -ketone-5-boric acid pinacol ester 无锡科华生物科技有限公司 2025-04-18 CN disclosed
CN-116396316-A Preparation method of 3-methylbenzo [ d ] oxazole-2 (3H) -ketone-5-boric acid pinacol ester 无锡科华生物科技有限公司 2023-07-07 CN disclosed