SCHEMBL29048452

SCHEMBL29048452

O=CCc1ccccc1N1C(=O)c2ccccc2C1=O

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NR1H3 Q13133 10/20 0.58
NR1H2 P55055 6/20 0.58
POLB P06746 1/20 0.47
CASP1 P29466 1/20 0.45
MGLL Q99685 1/20 0.42
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HTT P42858 1/20 0.40
CASP6 P55212 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27586782 0.81 NR1H3 (0.70) NR1H3NR1H2POLBMGLLMEN1
SCHEMBL6792489 0.78 NR1H3 (0.62) NR1H3NR1H2POLBCASP1MGLL
SCHEMBL31261698 0.78 NR1H3 (0.62) NR1H3NR1H2POLBCASP1MGLL
SCHEMBL9665968 0.78 NR1H2 (0.62) NR1H3NR1H2POLBCASP1MGLL
SCHEMBL4649466 0.76 POLB (0.65) NR1H3NR1H2POLBCASP1ALDH1A1
SCHEMBL5274870 0.76 KDM4E (0.42) NR1H3NR1H2MGLLKDM4EALDH1A1
SCHEMBL1904159 0.75 NR1H3 (0.68) NR1H3NR1H2POLBCASP1MGLL
SCHEMBL29616419 0.74 NR1H3 (1.00) NR1H3NR1H2POLBALDH1A1
SCHEMBL6690679 0.74 NR1H3 (0.61) NR1H3NR1H2POLBALDH1A1
SCHEMBL2464969 0.74 NR1H3 (1.00) NR1H3NR1H2POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114950558-B Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing hydrocarbon molecule benzyl site selective oxidation by using same 陕西师范大学 2023-08-11 CN disclosed
CN-114950558-A Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing benzyl-site selective oxidation of hydrocarbon molecules by using same 陕西师范大学 2022-08-30 CN disclosed