Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL29049203 | 0.95 | HSD17B10 (0.56) | HSD17B10MAPTTP53GAAMAPK1 | |
| Acetic Acid SCHEMBL29049224 | 0.95 | HSD17B10 (0.56) | HSD17B10MAPTTP53GAAMAPK1 | |
| Malonic Acid SCHEMBL29049213 | 0.94 | HSD17B10 (0.55) | HSD17B10MAPTTP53GAAMAPK1 | |
| SCHEMBL2232108 | 0.93 | HSD17B10 (0.60) | HSD17B10MAPTTP53GAAMAPK1 | |
| Propionic Acid SCHEMBL29049218 | 0.92 | HSD17B10 (0.54) | HSD17B10MAPTTP53GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL4373569 | 0.91 | HSD17B10 (0.58) | HSD17B10MAPTTP53GAAMAPK1 | |
| Iodide SCHEMBL29049215 | 0.91 | HSD17B10 (0.58) | HSD17B10MAPTTP53GAAMAPK1 | |
| Water SCHEMBL29049225 | 0.91 | HSD17B10 (0.58) | HSD17B10MAPTTP53GAAMAPK1 | |
| Ammonia Solution, Strong SCHEMBL28850909 | 0.91 | HSD17B10 (0.58) | HSD17B10MAPTTP53GAAMAPK1 | |
| Bromide SCHEMBL29049211 | 0.91 | HSD17B10 (0.58) | HSD17B10MAPTTP53GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114660896-B | Composition for forming silicon-containing resist underlayer film, pattern forming method, and silicon compound | 信越化学工业株式会社 | 2024-06-11 | — | — | CN | disclosed |
| CN-111208710-B | Iodine-containing thermosetting silicon-containing material, resist underlayer film forming composition for extreme ultraviolet lithography containing the same, and pattern forming method | 信越化学工业株式会社 | 2023-08-22 | — | — | CN | disclosed |
| CN-111458980-B | Composition for forming underlayer film of silicon-containing resist and method for forming pattern | 信越化学工业株式会社 | 2023-08-11 | — | — | CN | disclosed |