SCHEMBL29049335

SCHEMBL29049335

O=C(CCCCCN1C(=O)C/C(=C\c2ccccc2)C1=O)NO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ HDAC1 Q13547 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30526506 1.00 HDAC1 (1.00) HDAC1
SCHEMBL29049338 1.00 HDAC1 (1.00) HDAC1
SCHEMBL29049418 0.99 HDAC1 (1.00) HDAC1
SCHEMBL29049421 0.99 HDAC1 (1.00) HDAC1
SCHEMBL29049284 0.95 HDAC1 (1.00) HDAC1
SCHEMBL29049279 0.95 HDAC1 (1.00) HDAC1
SCHEMBL31412064 0.89 HDAC1 (0.80) HDAC1
SCHEMBL29049377 0.89 HDAC1 (0.80) HDAC1
SCHEMBL29049402 0.89 HDAC1 (0.80) HDAC1
SCHEMBL29049344 0.88 HDAC1 (1.00) HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124191-A1 HISTONE DEACETYLASE INHIBITOR AND USES THEREOF NANJING HONGSHUN PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) 2026-05-07 — — US disclosed
EP-4725940-A1 HISTONE DEACETYLASE INHIBITOR AND USE Nanjing Hongshun Pharmaceutical Technology Co., Ltd (CN) 2026-04-15 — — EP disclosed
WO-2025011398-A1 HISTONE DEACETYLASE INHIBITOR AND USE 南京市鸿舜医药科技有限公司 2025-01-16 — — WO disclosed
CN-116554079-B Histone deacetylase inhibitor and application thereof 南京市鸿舜医药科技有限公司 2023-11-10 — — CN disclosed
CN-116554079-A Histone deacetylase inhibitor and application thereof 南京市鸿舜医药科技有限公司 2023-08-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124191-A1 HISTONE DEACETYLASE INHIBITOR AND USES THEREOF HDAC1, HDAC3, HDAC2 HDAC1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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