Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31412129 | 1.00 | HDAC1 (0.67) | HDAC1MEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL29049399 | 0.96 | HDAC1 (0.68) | HDAC1 | |
| SCHEMBL29049384 | 0.96 | HDAC1 (0.68) | HDAC1 | |
| SCHEMBL29049310 | 0.95 | HDAC1 (0.69) | HDAC1 | |
| SCHEMBL31412027 | 0.95 | HDAC1 (0.69) | HDAC1 | |
| SCHEMBL29049340 | 0.95 | HDAC1 (0.69) | HDAC1 | |
| SCHEMBL29049403 | 0.95 | HDAC1 (0.69) | HDAC1 | |
| SCHEMBL29049308 | 0.95 | HDAC1 (0.69) | HDAC1 | |
| SCHEMBL29049318 | 0.95 | HDAC1 (0.69) | HDAC1 | |
| SCHEMBL29049397 | 0.86 | HDAC1 (0.79) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554079-B | Histone deacetylase inhibitor and application thereof | 南京市鸿舜医药科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116554079-A | Histone deacetylase inhibitor and application thereof | 南京市鸿舜医药科技有限公司 | 2023-08-08 | — | — | CN | disclosed |