⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL4041034 | 0.95 | SERPINE1 (0.33) | — | |
| SCHEMBL2968824 | 0.89 | EPHX1 (0.45) | — | |
| SCHEMBL28964356 | 0.87 | EPHX1 (0.48) | — | |
| SCHEMBL1585325 | 0.87 | EPHX1 (0.48) | — | |
| Ammonia Solution, Strong SCHEMBL669341 | 0.85 | EPHX1 (0.47) | — | |
| SCHEMBL5867973 | 0.79 | SERPINE1 (0.31) | — | |
| SCHEMBL4674791 | 0.77 | — | — | |
| SCHEMBL126557 | 0.75 | SERPINE1 (0.38) | — | |
| SCHEMBL26834 | 0.75 | SERPINE1 (0.38) | — | |
| SCHEMBL1138479 | 0.75 | SERPINE1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4729513-A1 | A-KETO ACID AMIDE OR SUBSTITUTED OXALIC ACID AMIDE ESTER COMPOUND AND COMPOSITION THEREOF | Nanjing Chempion Biotechnology Co., Ltd. (CN) | 2026-04-22 | — | — | EP | disclosed |
| WO-2025001687-A1 | Α-KETO ACID AMIDE OR SUBSTITUTED OXALIC ACID AMIDE ESTER COMPOUND AND COMPOSITION THEREOF | 南京桦冠生物技术有限公司 | 2025-01-02 | — | — | WO | disclosed |
| CN-116554122-B | Alpha-keto acid amide or substituted oxalic acid amide ester compound and composition thereof | 南京桦冠生物技术有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116554122-A | Alpha-keto acid amide or substituted oxalic acid amide ester compound and composition thereof | 南京桦冠生物技术有限公司 | 2023-08-08 | — | — | CN | disclosed |