Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.67 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | RAF1 | P04049 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25400992 | 0.94 | KRAS (0.70) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30537095 | 0.94 | KRAS (0.70) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30810155 | 0.92 | KRAS (0.69) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL27243193 | 0.92 | KRAS (0.69) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL29049543 | 0.91 | KRAS (0.56) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30229732 | 0.91 | KRAS (0.70) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30238100 | 0.91 | KRAS (0.67) | KRAS | |
| SCHEMBL25046922 | 0.91 | KRAS (0.67) | KRAS | |
| SCHEMBL29049539 | 0.91 | KRAS (0.80) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25437473 | 0.90 | KRAS (0.68) | KRASMAPK3MAPK1RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514846-A | Heterocyclic derivative, preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2023-08-01 | — | — | CN | disclosed |