Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.85 |
| ▸ | TENT4A | Q5XG87 | 1/20 | 0.85 |
| ▸ | TENT4B | Q8NDF8 | 1/20 | 0.85 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29070749 | 1.00 | CYP2B6 (0.85) | CYP2B6TENT4ATENT4BMEN1ALDH1A1 | |
| SCHEMBL21327293 | 0.93 | CYP2B6 (0.83) | CYP2B6TENT4ATENT4BMEN1ALDH1A1 | |
| SCHEMBL29714618 | 0.93 | CYP2B6 (0.83) | CYP2B6TENT4ATENT4BMEN1ALDH1A1 | |
| SCHEMBL22952278 | 0.93 | CYP2B6 (0.83) | CYP2B6TENT4ATENT4BMEN1ALDH1A1 | |
| SCHEMBL30084996 | 0.93 | CYP2B6 (0.83) | CYP2B6TENT4ATENT4BMEN1ALDH1A1 | |
| SCHEMBL22952841 | 0.93 | CYP2B6 (0.83) | CYP2B6TENT4ATENT4B | |
| SCHEMBL21327150 | 0.93 | CYP2B6 (0.88) | CYP2B6TENT4ATENT4B | |
| SCHEMBL29714547 | 0.93 | CYP2B6 (0.88) | CYP2B6TENT4ATENT4B | |
| SCHEMBL22952848 | 0.93 | CYP2B6 (0.81) | CYP2B6TENT4ATENT4B | |
| SCHEMBL30084997 | 0.93 | CYP2B6 (0.81) | CYP2B6TENT4ATENT4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751200-A | Tricyclic compounds containing substituted pyridones and methods of using the same | 爱彼特生物制药公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-110114071-B | Tricyclic compounds containing substituted pyridones and methods of using the same | 爱彼特生物制药公司 | 2023-07-04 | — | — | CN | disclosed |
| EP-3534903-B1 | SUBSTITUTED PYRIDINONE-CONTAINING TRICYCLIC COMPOUNDS, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (CA) | 2022-08-03 | — | — | EP | disclosed |