Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | CDC25B | P30305 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358307 | 1.00 | MEN1 (0.53) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29051125 | 1.00 | MEN1 (0.53) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29051131 | 0.92 | MEN1 (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL28361829 | 0.92 | MEN1 (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29051128 | 0.92 | MEN1 (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29051074 | 0.91 | PTPN2 (0.55) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL28361881 | 0.91 | PTPN2 (0.55) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL28361865 | 0.91 | PTPN2 (0.55) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29051136 | 0.91 | PTPN2 (0.55) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29051090 | 0.91 | PTPN2 (0.55) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746355-B | Phenylpyrazole compound, pharmaceutical composition, and preparation method and application thereof | 中国科学院上海有机化学研究所 | 2023-08-11 | — | — | CN | disclosed |