Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 15/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 3/20 | 0.42 |
| ▸ | WEE1 | P30291 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29051789 | 0.89 | WEE1 (0.45) | PTK2BTKWEE1 | |
| SCHEMBL29051707 | 0.89 | PTK2 (0.46) | PTK2PTK2BWEE1 | |
| Hydrochloric Acid SCHEMBL29051821 | 0.86 | PTK2 (0.45) | PTK2PTK2BBTKWEE1 | |
| SCHEMBL29051916 | 0.85 | STK17B (0.46) | PTK2PTK2BWEE1 | |
| SCHEMBL30468400 | 0.84 | PTK2 (0.45) | PTK2PTK2BBTKWEE1 | |
| Hydrochloric Acid SCHEMBL29051784 | 0.84 | PTK2 (0.44) | PTK2PTK2BBTKWEE1 | |
| SCHEMBL30468423 | 0.81 | PTK2 (0.54) | PTK2PTK2BWEE1 | |
| Hydrochloric Acid SCHEMBL29051834 | 0.80 | PTK2 (0.53) | PTK2PTK2BWEE1 | |
| SCHEMBL29051801 | 0.80 | PTK2 (0.50) | PTK2PTK2BBTK | |
| SCHEMBL29051688 | 0.79 | ALK (0.43) | PTK2PTK2BWEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332910-A | 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof | 江苏威凯尔医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |