SCHEMBL29051963

SCHEMBL29051963

O=C(O)Cc1c(Cl)ccc(O)c1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 3/20 0.61
CA2 P00918 2/20 0.53
CYP3A4 P08684 1/20 0.48
MAPK1 P28482 1/20 0.48
GAA P10253 3/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALDH1A1 P00352 2/20 0.46
GLA P06280 1/20 0.46
TSHR P16473 3/20 0.44
POLB P06746 2/20 0.44
NFKB1 P19838 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
RGS12 O14924 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
APEX1 P27695 1/20 0.44
THPO P40225 1/20 0.44
BLM P54132 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55504 0.87 AKR1B1 (0.65) AKR1B1CA2CYP3A4MAPK1GAA
SCHEMBL29397431 0.87 AKR1B1 (0.65) AKR1B1CA2CYP3A4MAPK1GAA
SCHEMBL1701239 0.87 AKR1B1 (0.65) AKR1B1CA2CYP3A4MAPK1GAA
SCHEMBL3234019 0.85 AKR1B1 (0.63) AKR1B1CA2CYP3A4MAPK1GAA
Ammonia Solution, Strong SCHEMBL2688772 0.85 AKR1B1 (0.63) AKR1B1CA2CYP3A4MAPK1GAA
Ammonia Solution, Strong SCHEMBL25360718 0.85 AKR1B1 (0.63) AKR1B1CA2CYP3A4MAPK1GAA
Hydrochloric Acid SCHEMBL29008321 0.85 AKR1B1 (0.63) AKR1B1CA2GAAKDM4EHPGD
SCHEMBL18191140 0.81 AKR1B1 (0.63) AKR1B1CA2GAAKDM4EHPGD
SCHEMBL2239127 0.80 AKR1B1 (0.57) AKR1B1CA2GAAKDM4EALDH1A1
Dimethylamine SCHEMBL31349920 0.80 AKR1B1 (0.57) AKR1B1CA2KDM4EALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116338026-A Liquid chromatography tandem mass spectrometry detection method for detecting pesticides and metabolites thereof in protein-containing body fluid 华南农业大学 2023-06-27 CN claimed
CN-116338026-A Liquid chromatography tandem mass spectrometry detection method for detecting pesticides and metabolites thereof in protein-containing body fluid 华南农业大学 2023-06-27 CN disclosed