Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28556326 | 0.89 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10DRD3PIK3CG | |
| SCHEMBL28700344 | 0.85 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10PIK3CGHPGD | |
| SCHEMBL28563278 | 0.85 | HSD17B10 (0.55) | KDM4EALDH1A1HSD17B10DRD3PIK3CG | |
| 4-N-Acetyl-1-Piperazinyl-Norfloxacin SCHEMBL30570718 | 0.83 | HSD17B10 (0.83) | KDM4EALDH1A1HSD17B10DRD3PIK3CG | |
| 4-N-Acetyl-1-Piperazinyl-Norfloxacin SCHEMBL11027379 | 0.83 | HSD17B10 (0.83) | KDM4EALDH1A1HSD17B10DRD3PIK3CG | |
| SCHEMBL28423003 | 0.79 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10PIK3CGHPGD | |
| SCHEMBL28414785 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10DRD3PIK3CG | |
| SCHEMBL22698592 | 0.78 | HSD17B10 (0.84) | KDM4EALDH1A1HSD17B10DRD3PIK3CG | |
| SCHEMBL1243569 | 0.78 | MEN1 (0.68) | KDM4EALDH1A1HSD17B10DRD3PIK3CG | |
| SCHEMBL28559532 | 0.77 | HSD17B10 (0.58) | KDM4EALDH1A1HSD17B10DRD3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824389-B | Acrylic ketone derivative of N-acetylnorfloxacin and preparation method and application thereof | 河南大学 | 2023-08-15 | — | — | CN | disclosed |