Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 16/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29054934 | 1.00 | HDAC1 (0.61) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL30537338 | 1.00 | HDAC1 (0.61) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL30537328 | 1.00 | HDAC1 (0.61) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL29054829 | 0.99 | HDAC1 (0.60) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL30537363 | 0.99 | HDAC1 (0.60) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL29054842 | 0.95 | HDAC1 (0.55) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL30537360 | 0.95 | HDAC1 (0.55) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL30537352 | 0.87 | HDAC1 (0.62) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL29054861 | 0.87 | HDAC1 (0.62) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL30537331 | 0.87 | HDAC1 (0.62) | HDAC1HDAC6HDAC8HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621801-A | Coumarin derivative and preparation method and application thereof | 暨南大学 | 2023-08-22 | — | — | CN | disclosed |