Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GALK1 | P51570 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 12/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30501013 | 1.00 | NPC1 (0.53) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10057965 | 1.00 | NPC1 (0.53) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10057971 | 0.97 | MEN1 (0.50) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10057685 | 0.97 | NPC1 (0.50) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10057964 | 0.97 | MEN1 (0.50) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10057974 | 0.95 | MEN1 (0.49) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10057532 | 0.95 | MEN1 (0.53) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10057531 | 0.92 | MEN1 (0.50) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10057533 | 0.92 | MEN1 (0.50) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10057536 | 0.92 | MEN1 (0.50) | NPC1MAPTRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462579-B | Preparation method of spirofluorene anthrone compound | 大连理工大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-116462579-A | Preparation method of spirofluorene anthrone compound | 大连理工大学 | 2023-07-21 | — | — | CN | disclosed |