Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.34 |
| ▸ | SLC2A3 | P11169 | 4/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29056227 | 0.91 | SLC22A12 (0.44) | KDM4EPDE4BSLC22A12MAOBGRM5 | |
| SCHEMBL29056276 | 0.87 | SLC22A12 (0.45) | KDM4EPDE4BSLC22A12BRD4KCNH2 | |
| SCHEMBL29056210 | 0.81 | KDM4E (0.40) | KDM4EPDE4BSLC2A1SLC2A3MAOB | |
| SCHEMBL29056248 | 0.80 | PDE4B (0.40) | KDM4EPDE4BSLC22A12SLC2A1SLC2A3 | |
| SCHEMBL30542634 | 0.80 | PDE4B (0.47) | KDM4EPDE4BGRM5BRD4CREBBP | |
| SCHEMBL29056211 | 0.80 | PDE4B (0.47) | KDM4EPDE4BGRM5BRD4CREBBP | |
| SCHEMBL29056228 | 0.79 | SLC22A12 (0.55) | KDM4EPDE4BSLC22A12BRD4CREBBP | |
| SCHEMBL29056193 | 0.78 | PDE4B (0.48) | KDM4EPDE4BSLC2A1SLC2A3JAK2 | |
| SCHEMBL29056254 | 0.77 | ABCG2 (0.52) | KDM4ESLC22A12EGFRKDR | |
| SCHEMBL29056279 | 0.77 | PDE4B (0.40) | KDM4EPDE4BSLC2A1SLC2A3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640095-A | Diaryl amine derivative containing aliphatic carboxyl and preparation method and application thereof | 山东大学 | 2023-08-25 | — | — | CN | disclosed |