Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29057286 | 0.94 | TLR7 (0.40) | TLR7TLR8MTNR1AMTNR1BTSHR | |
| SCHEMBL29320220 | 0.91 | TLR8 (0.37) | TLR7TLR8NAMPT | |
| SCHEMBL30539861 | 0.91 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL29320192 | 0.90 | TLR7 (0.39) | TLR7TLR8MTNR1AMTNR1BNAMPT | |
| SCHEMBL23037710 | 0.89 | TLR7 (0.40) | TLR7TLR8NAMPT | |
| SCHEMBL29322691 | 0.88 | TLR8 (0.35) | TLR7TLR8NAMPT | |
| SCHEMBL29320204 | 0.88 | TLR7 (0.38) | TLR7TLR8NAMPTKDM4EMAPT | |
| SCHEMBL30539846 | 0.88 | TLR8 (0.38) | TLR7TLR8NAMPT | |
| SCHEMBL23037589 | 0.88 | TLR8 (0.38) | TLR7TLR8NAMPT | |
| SCHEMBL29315509 | 0.87 | TLR7 (0.39) | TLR7TLR8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521387-B | NLRP3 modulators | 先天肿瘤免疫公司 | 2023-08-22 | — | — | CN | disclosed |