Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 14/20 | 0.77 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29057450 | 1.00 | OGA (0.77) | OGAATMMAPTHRH3ALDH1A1 | |
| SCHEMBL29057480 | 1.00 | OGA (0.77) | OGAATMMAPTHRH3ALDH1A1 | |
| SCHEMBL29057427 | 0.91 | OGA (0.77) | OGAATMALDH1A1 | |
| SCHEMBL29057518 | 0.91 | OGA (0.77) | OGAALDH1A1SMN1; SMN2 | |
| SCHEMBL29057492 | 0.88 | OGA (0.79) | OGAATMHRH3 | |
| SCHEMBL27008577 | 0.87 | OGA (1.00) | OGA | |
| SCHEMBL27022324 | 0.87 | OGA (1.00) | OGA | |
| SCHEMBL27022399 | 0.87 | OGA (1.00) | OGA | |
| SCHEMBL29057470 | 0.85 | OGA (0.81) | OGAMAPTHRH3ALDH1A1TSHR | |
| SCHEMBL29057423 | 0.85 | OGA (0.72) | OGAATMMAPTALDH1A1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438167-A | Compounds having O-GlcNAc enzyme inhibitory activity and uses thereof | 美迪福伦DBT有限公司 | 2023-07-14 | — | — | CN | disclosed |