Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 9/20 | 0.78 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TXK | P42681 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | ITK | Q08881 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29057413 | 0.89 | OGA (0.64) | OGAACKR3HTTSMN1; SMN2 | |
| SCHEMBL27022520 | 0.88 | OGA (1.00) | OGAHTTSMN1; SMN2 | |
| SCHEMBL29057440 | 0.83 | OGA (0.59) | OGAACKR3HTTSMN1; SMN2 | |
| SCHEMBL16113885 | 0.82 | OGA (0.73) | OGAACKR3HTTSMN1; SMN2 | |
| SCHEMBL29057545 | 0.82 | OGA (0.73) | OGAACKR3NPSR1 | |
| SCHEMBL29057544 | 0.81 | OGA (0.58) | OGAHTTSMN1; SMN2 | |
| SCHEMBL29057529 | 0.80 | OGA (0.79) | OGAACKR3SMN1; SMN2 | |
| SCHEMBL29057496 | 0.80 | OGA (0.78) | OGASMN1; SMN2 | |
| SCHEMBL29057511 | 0.80 | OGA (0.78) | OGASMN1; SMN2 | |
| Lithium Ion SCHEMBL29057495 | 0.80 | SMN1; SMN2 (0.53) | OGAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438167-A | Compounds having O-GlcNAc enzyme inhibitory activity and uses thereof | 美迪福伦DBT有限公司 | 2023-07-14 | — | — | CN | disclosed |