Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29058661 | 0.86 | EPAS1 (0.80) | EPAS1MAPTPOLBLMNASMN1; SMN2 | |
| SCHEMBL29058656 | 0.86 | EPAS1 (0.78) | EPAS1MAPTPOLBLMNAHPGD | |
| SCHEMBL29059359 | 0.85 | EPAS1 (1.00) | EPAS1MAPTPOLBLMNAHPGD | |
| SCHEMBL29059021 | 0.85 | EPAS1 (0.81) | EPAS1MAPTPOLBLMNASMN1; SMN2 | |
| SCHEMBL30395450 | 0.84 | EPAS1 (1.00) | EPAS1MAPTPOLBLMNAHPGD | |
| SCHEMBL30396182 | 0.83 | EPAS1 (0.74) | EPAS1MAPTPOLBLMNAHPGD | |
| SCHEMBL29058654 | 0.83 | EPAS1 (0.74) | EPAS1MAPTPOLBLMNAHPGD | |
| SCHEMBL7824661 | 0.83 | EPAS1 (0.66) | EPAS1MAPTPOLBLMNASMN1; SMN2 | |
| SCHEMBL29058667 | 0.82 | EPAS1 (0.81) | EPAS1MAPTPOLBLMNASMN1; SMN2 | |
| SCHEMBL30395324 | 0.81 | EPAS1 (0.64) | EPAS1MAPTPOLBLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116236478-A | Application of aromatic heterocyclic formamide compound | 浙江大学 | 2023-06-09 | — | — | CN | disclosed |