SCHEMBL2905973

SCHEMBL2905973

CC(=O)OC(C(=O)O)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
CYP2D6 P10635 1/20 0.46
KCNN4 O15554 1/20 0.44
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
CES1 P23141 2/20 0.40
ALDH1A1 P00352 4/20 0.39
ALOX15 P16050 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL8673561 0.89 CYP1A2 (0.39) CYP1A2CYP2D6KCNN4CYP2C19HIF1A
SCHEMBL11061722 0.86 KCNN4 (0.42) CYP1A2CYP2D6KCNN4CYP2C19HIF1A
SCHEMBL10693506 0.84 MAPT (0.52) CYP1A2CYP2D6KCNN4CYP2C19HIF1A
SCHEMBL5071053 0.82 KCNN4 (0.44) CYP1A2CYP2D6KCNN4CYP2C19HIF1A
SCHEMBL8894764 0.82 CYP2C19 (0.47) CYP1A2CYP2D6KCNN4CYP2C19HIF1A
SCHEMBL5322361 0.82 CYP2C19 (0.47) CYP1A2CYP2D6KCNN4CYP2C19HIF1A
SCHEMBL27264493 0.81 KCNN4 (0.39) CYP1A2CYP2D6KCNN4CYP2C19HIF1A
SCHEMBL9876860 0.79 CES1 (0.48) CYP1A2CYP2D6KCNN4CYP2C19HIF1A
SCHEMBL340836 0.78 KCNN4 (0.52) CYP1A2CYP2D6KCNN4CYP2C19HIF1A
SCHEMBL5666953 0.78 KCNN4 (0.47) CYP1A2CYP2D6KCNN4CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7452545-B2 Oligosaccharide aldonic acids and their topical use YU RUEY J 2008-11-18 US claimed
US-20080090772-A1 Oligosaccharide Aldonic Acids and Their Topical Use YU RUEY J 2008-04-17 US claimed
EP-1685843-A1 Oligosaccharide aldonic acids and their topical use Yu, Ruey J., Dr. (US) 2006-08-02 EP claimed
EP-1227820-B1 OLIGOSACCHARIDE ALDONIC ACIDS AND THEIR TOPICAL USE YU RUEY J (US) 2006-04-19 EP claimed
US-20050171194-A1 Enlargement of mucocutaneous or cutaneous organs and sites with topical compositions YU RUEY J (US) 2005-08-04 US claimed
WO-2005055947-A2 ENLARGEMENT OF MUCOCUTANEOUS OR CUTANEOUS ORGANS AND SITES WITH TOPICAL COMPOSITIONS YU RUEY J (US) 2005-06-23 WO claimed
US-20040180854-A1 Oligosaccharide aldonic acids and their topical use YU RUEY J (US) 2004-09-16 US claimed
US-6740327-B2 USE FOR COSMETIC AND DERMATOLOGICAL INDICATIONS, REDUCING AND SOOTHING MUCOSA AND SKIN ERYTHEMA, INFLAMMATION OR REACTION CAUSED BY INTERNAL OR EXTERNAL FACTORS, WOUND HEALING, ETC. YU RUEY J (US) 2004-05-25 US claimed
EP-1227820-A2 OLIGOSACCHARIDE ALDONIC ACIDS AND THEIR TOPICAL USE Yu, Ruey J., Dr. (US) 2002-08-07 EP claimed
US-20020028227-A1 Oligosaccharide aldonic acids and their topical use YU RUEY J (US) 2002-03-07 US claimed
WO-2001001932-A2 OLIGOSACCHARIDE ALDONIC ACIDS AND THEIR TOPICAL USE YU RUEY J (US) 2001-01-11 WO claimed
US-6054479-A FOR FOOD, COSMETICS, DRUGS; ADDING ARYL ACETOXYACETIC ACID TRISTRATA, INC. (A DELAWARE CORPORATION) (US) 2000-04-25 US claimed
US-6046238-A TOPICALLY APPLYING TO AN AFFECTED AREA OF SKIN AN EFFECTIVE AMOUNT OF ARYL 2-ACETOXYETHANOIC ACID, EFFECTIVE TO REMOVE OR PREVENT THE SPREAD OF ACNE VULGARIS TRISTRATA, INC. (US) 2000-04-04 US claimed
US-5958975-A REVERSING OR PREVENTING TACHYPHYLAXIS OF PSORIASIS TO A CORTICOSTEROID; APPLYING TO PSORIATIC SKIN A CORTICOSTEROID AND AN ARYL 2-ACETOXY-ETHANOIC ACID; COSMETICS; FOODS TRISTRATA, INC. (US) 1999-09-28 US claimed
US-5874071-A USING AN ARYL 2-ACETOXYETHANOIC ACID; DEODERANTS; ANTIPRESPIRANTS; PREVENTION OF ODORS ASSOCIATED WITH FOOT, SCALP, SKIN, NAILS AND FOLLICULR INFECTIONS; PROPIONIBACTERIUM ACNES; FOODS; COSMETICS; DRUGS TRISTRATA, INC. (US) 1999-02-23 US claimed
US-5807890-A USING ARYL 2-ACETOXYETHANOIC ACID TRISTRATA, INC. (US) 1998-09-15 US claimed
EP-0789553-A4 ANTIODOR, ANTIMICROBIAL AND PRESERVATIVE COMPOSITIONS AND METHODS OF USING SAME TRISTRATA INC (US) 1998-05-06 EP claimed
EP-0789553-A1 ANTIODOR, ANTIMICROBIAL AND PRESERVATIVE COMPOSITIONS AND METHODS OF USING SAME Tristrata, Inc. (US) 1997-08-20 EP claimed
US-5641475-A INCLUDES ARYL 2-ACETOXYETHANOIC ACID AS SYNERGIST OR AMPLIFIER TRISTRATA, INC. (US) 1997-06-24 US claimed
WO-1996013247-A1 ANTIODOR, ANTIMICROBIAL AND PRESERVATIVE COMPOSITIONS AND METHODS OF USING SAME TRISTRATA, INC. (US) 1996-05-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080090772-A1 Oligosaccharide Aldonic Acids and Their Topical Use GLA, ALDOA, MAN2A1 CYP1A2 2524/4885CYP2D6 2918/4885KCNN4 3806/4885
US-20020028227-A1 Oligosaccharide aldonic acids and their topical use GLA, ALDOA, MAN2A1 CYP1A2 2524/4885CYP2D6 2918/4885KCNN4 3806/4885
US-20040180854-A1 Oligosaccharide aldonic acids and their topical use GLA, ALDOA, MAN2A1 CYP1A2 2524/4885CYP2D6 2918/4885KCNN4 3806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.