Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 19/20 | 1.00 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29059731 | 0.92 | ANO1 (1.00) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL30489873 | 0.92 | ANO1 (1.00) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL29059597 | 0.90 | ANO1 (1.00) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL29059595 | 0.89 | ANO1 (1.00) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL29059770 | 0.88 | ANO1 (1.00) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL30489869 | 0.88 | ANO1 (1.00) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL12314194 | 0.85 | MEN1 (0.84) | ANO1ANO2MEN1KMT2A | |
| SCHEMBL29059776 | 0.84 | ANO1 (1.00) | ANO1ANO2 | |
| SCHEMBL29059589 | 0.84 | ANO1 (1.00) | ANO1ANO2 | |
| SCHEMBL29059727 | 0.82 | ANO1 (1.00) | ANO1ANO2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444481-A | 4-arylthiophene carboxylic acid compounds as ANO1 protein inhibitors | 北京大学 | 2023-07-18 | — | — | CN | claimed |
| CN-116444481-A | 4-arylthiophene carboxylic acid compounds as ANO1 protein inhibitors | 北京大学 | 2023-07-18 | — | — | CN | disclosed |