Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 8/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29060896 | 0.86 | PNP (0.57) | PNPADORA2AADORA2BLTB4RADORA3 | |
| SCHEMBL29060886 | 0.84 | PNP (0.55) | PNPADORA2AADORA2BLTB4RADORA3 | |
| SCHEMBL29060909 | 0.84 | PNP (0.55) | PNPADORA2AADORA2BLTB4RADORA3 | |
| SCHEMBL29060904 | 0.84 | PNP (0.55) | PNPADORA2AADORA2BLTB4RADORA3 | |
| SCHEMBL29060931 | 0.84 | PNP (0.55) | PNPADORA2AADORA2BLTB4RADORA3 | |
| SCHEMBL29060929 | 0.84 | PNP (0.55) | PNPADORA2AADORA2BLTB4RADORA3 | |
| SCHEMBL29060919 | 0.84 | PNP (0.55) | PNPADORA2AADORA2BLTB4RADORA3 | |
| SCHEMBL29060889 | 0.82 | PNP (0.53) | PNPADORA2AADORA2BLTB4RADORA3 | |
| SCHEMBL29060887 | 0.80 | PNP (0.54) | PNPADORA2AADORA2BLTB4RKDM4E | |
| SCHEMBL29060910 | 0.80 | PNP (0.51) | PNPADORA2AADORA2BLTB4RADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116492347-A | Compound for activating AMPK and application thereof | 华安医学股份有限公司 | 2023-07-28 | — | — | CN | disclosed |