⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL575170 | 0.84 | — | — | |
| SCHEMBL612569 | 0.80 | — | — | |
| SCHEMBL24159 | 0.80 | — | — | |
| SCHEMBL1710977 | 0.80 | — | — | |
| SCHEMBL29494 | 0.76 | — | — | |
| SCHEMBL5247669 | 0.74 | — | — | |
| SCHEMBL10712112 | 0.63 | — | — | |
| SCHEMBL18112448 | 0.60 | — | — | |
| SCHEMBL16860545 | 0.60 | TRIM24 (0.38) | — | |
| SCHEMBL31232329 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 388 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590768-A | Heterocyclic compounds, compositions thereof and their use as anti-influenza virus agents | 银杏树药业(苏州)有限公司 | 2019-12-20 | — | — | CN | claimed |
| CN-108242566-A | Electrolyte solution and secondary battery | 宁德时代新能源科技股份有限公司 | 2018-07-03 | — | — | CN | claimed |
| CN-103380122-B | Novel benzodioxole piperazine compounds | HOFFMANN LA ROCHE | 2015-04-29 | — | — | CN | claimed |
| US-8722683-B2 | Benzodioxole piperazine compounds | HOFFMANN LA-ROCHE INC. (US) | 2014-05-13 | — | — | US | claimed |
| EP-2675798-A1 | NOVEL BENZODIOXOLE PIPERAZINE COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-12-25 | — | — | EP | claimed |
| CN-103380122-A | Novel benzodioxole piperazine compounds | HOFFMANN LA ROCHE | 2013-10-30 | — | — | CN | claimed |
| US-20130040948-A1 | NOVEL BENZODIOXOLE PIPERAZINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-02-14 | — | — | US | claimed |
| WO-2012110470-A1 | NOVEL BENZODIOXOLE PIPERAZINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-08-23 | — | — | WO | claimed |
| CN-115197086-B | Preparation method of difluoromethoxy-containing m-diamide compound | 南通泰禾化工股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| US-20240132505-A1 | PYRROLOPYRIMIDINE ITK INHIBITORS | ACLARIS THERAPEUTICS, INC. | 2024-04-25 | — | — | US | disclosed |
| US-20240101521-A1 | DIAMINOTRIAZINE COMPOUNDS | BASF SE (DE) | 2024-03-28 | — | — | US | disclosed |
| US-20240067643-A1 | SUBSTITUTED PYRROLOPYRIDINE JAK INHIBITORS AND METHODS OF MAKING AND USING THE SAME | ACLARIS THERAPEUTICS, INC. | 2024-02-29 | — | — | US | disclosed |
| WO-2024015425-A1 | HERBICIDAL BENZOXAZINES | FMC CORPORATION (US) | 2024-01-18 | — | — | WO | disclosed |
| US-11820775-B2 | Pyrrolopyrimidine ITK inhibitors | ACLARIS THERAPEUTICS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| EP-0012366-B1 | 3,4-DIAZA-BICYCLO(4.1.0)HEPTEN-2-ONES-5, PROCESS FOR THEIR PREPARATION AND THERAPEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1984-03-14 | — | — | EP | disclosed |
| US-4410529-A | HYPOTENSIVE AGNENTS, ANTICOAGULANTS | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-18 | — | — | US | disclosed |
| EP-0042107-A1 | Dihydropyridazinones, processes for their preparation and pharmaceutical compositions containing these compounds | BASF Aktiengesellschaft (DE) | 1981-12-23 | — | — | EP | disclosed |
| US-4271163-A | HYPOTENSIVE AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1981-06-02 | — | — | US | disclosed |
| EP-0012366-A1 | 3,4-Diaza-bicyclo(4.1.0)hepten-2-ones-5, process for their preparation and therapeutical compositions containing them | BASF Aktiengesellschaft (DE) | 1980-06-25 | — | — | EP | disclosed |
| US-4059615-A | INSECTICIDE, POLYMER INTERMEDIATE | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |