Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 8/20 | 0.65 |
| ▸ | SCN8A | Q9UQD0 | 7/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30530053 | 1.00 | SCN10A (0.65) | SCN10ASCN8A | |
| SCHEMBL29062028 | 0.91 | SCN10A (0.67) | SCN10ASCN8A | |
| SCHEMBL30530118 | 0.91 | SCN10A (0.67) | SCN10ASCN8A | |
| SCHEMBL30530124 | 0.91 | SCN10A (0.67) | SCN10ASCN8A | |
| SCHEMBL29062010 | 0.91 | SCN10A (0.67) | SCN10ASCN8A | |
| SCHEMBL25373823 | 0.89 | SCN10A (0.65) | SCN10ASCN8A | |
| SCHEMBL29061993 | 0.88 | SCN10A (0.64) | SCN10ASCN8A | |
| SCHEMBL30530082 | 0.88 | SCN10A (0.64) | SCN10ASCN8A | |
| SCHEMBL29062019 | 0.88 | SCN10A (0.63) | SCN10ASCN8A | |
| SCHEMBL30530142 | 0.88 | SCN10A (0.63) | SCN10ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655497-A | Amidine derivative compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2023-08-29 | — | — | CN | disclosed |