Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906250 | 0.89 | PTGDR2 (0.48) | PTGDR2KMT2AMAPTLMNAHTT | |
| SCHEMBL1992776 | 0.86 | MAPT (0.49) | PTGDR2KMT2AMAPTLMNAHTT | |
| SCHEMBL1992769 | 0.84 | PTGDR2 (0.73) | PTGDR2 | |
| SCHEMBL1994283 | 0.81 | KMT2A (0.46) | PTGDR2KMT2AMAPTLMNAHTT | |
| SCHEMBL1996821 | 0.80 | PTGDR2 (0.47) | PTGDR2POLBRORCALDH1A1 | |
| SCHEMBL2347435 | 0.79 | MAPT (0.41) | PTGDR2KMT2AMAPTLMNAHTT | |
| SCHEMBL1994155 | 0.75 | PTGDR2 (0.51) | PTGDR2KMT2AMAPTLMNAHTT | |
| SCHEMBL1991223 | 0.73 | PTGDR2 (0.52) | PTGDR2 | |
| SCHEMBL1997126 | 0.72 | PTGDR2 (0.74) | PTGDR2 | |
| SCHEMBL2902261 | 0.70 | PTGDR2 (0.41) | PTGDR2KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937633-B1 | BIPHENYLOXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASE | ASTRAZENECA AB (SE) | 2010-08-04 | — | — | EP | disclosed |