Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.46 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15564132 | 1.00 | BTK (0.47) | BTKDYRK3ROCK2PRKD3MAP4K4 | |
| SCHEMBL28097476 | 1.00 | BTK (0.47) | BTKDYRK3ROCK2PRKD3MAP4K4 | |
| SCHEMBL29064399 | 0.87 | BTK (0.39) | BTKFGFR1FGFR4LCKFYN | |
| SCHEMBL29064397 | 0.87 | BTK (0.39) | BTKFGFR1FGFR4LCKFYN | |
| SCHEMBL13858252 | 0.85 | BTK (0.47) | BTKFGFR1FGFR4SRC | |
| SCHEMBL13858254 | 0.85 | BTK (0.47) | BTKFGFR1FGFR4SRC | |
| SCHEMBL16769872 | 0.85 | BTK (0.47) | BTKFGFR1FGFR4SRC | |
| SCHEMBL20981724 | 0.81 | FLT3 (0.42) | BTKDYRK3ROCK2PRKD3MAP4K4 | |
| SCHEMBL15515675 | 0.80 | BTK (0.53) | BTKDYRK3PRKD3MAP4K4PRKACA | |
| SCHEMBL13860235 | 0.80 | BTK (0.53) | BTKDYRK3PRKD3MAP4K4PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514806-A | Biological inhibitor containing acrylketone, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |