Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | BCL6 | P41182 | 1/20 | 0.46 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580186 | 1.00 | KAT2B (0.53) | KAT2BALDH1A1BCL6BCORPOLB | |
| SCHEMBL9771638 | 0.89 | KAT2B (0.56) | KAT2BALDH1A1BCL6BCORPOLB | |
| SCHEMBL17819079 | 0.84 | KAT2B (0.56) | KAT2BALDH1A1POLBNPC1RAB9A | |
| SCHEMBL29064877 | 0.82 | KAT2B (0.50) | KAT2BALDH1A1BCL6BCORPOLB | |
| SCHEMBL4861914 | 0.82 | KAT2B (0.72) | KAT2BALDH1A1BCL6BCORPOLB | |
| SCHEMBL1465402 | 0.82 | KAT2B (0.50) | KAT2BALDH1A1BCL6BCORPOLB | |
| SCHEMBL29580949 | 0.82 | KAT2B (0.50) | KAT2BALDH1A1BCL6BCORPOLB | |
| SCHEMBL21793740 | 0.81 | HPGD (0.48) | KAT2BALDH1A1POLBNPC1RAB9A | |
| SCHEMBL1421193 | 0.81 | KAT2B (0.52) | KAT2BALDH1A1POLBNPC1RAB9A | |
| SCHEMBL4619073 | 0.79 | KAT2B (0.51) | KAT2BALDH1A1POLBRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528867-A | Compounds for the treatment of Alzheimer's disease | 艾伯塔大学理事会 | 2023-08-01 | — | — | CN | disclosed |