Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL29065267

CCCC(=O)[C@@H](N)CC(C)C.O=C(O)C(F)(F)F

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.47
ANPEP P15144 3/20 0.40
RNPEP Q9H4A4 3/20 0.40
DNPEP Q9ULA0 2/20 0.40
SLC1A3 P43003 2/20 0.38
SLC1A2 P43004 2/20 0.38
S1PR1 P21453 5/20 0.37
S1PR3 Q99500 5/20 0.37
S1PR2 O95136 4/20 0.37
S1PR5 Q9H228 3/20 0.37
LARS1 Q9P2J5 1/20 0.35
SCN9A Q15858 4/20 0.35
ELANE P08246 1/20 0.34
GRIK1 P39086 1/20 0.33
SLC1A1 P43005 1/20 0.33
GRIK2 Q13002 1/20 0.33
DPP4 P27487 1/20 0.33
DPP8 Q6V1X1 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
CTSL P07711 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28866572 0.87 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
SCHEMBL13499200 0.87 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Leucine SCHEMBL7441032 0.80 SLC7A5 (0.75) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Leucine SCHEMBL6659926 0.80 SLC7A5 (0.75) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Leucine SCHEMBL31651400 0.80 SLC7A5 (0.75) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Leucine Amide SCHEMBL22042976 0.78 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Leucinamide SCHEMBL22042928 0.78 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Leucinamide SCHEMBL22042925 0.78 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Leucine Amide SCHEMBL3054048 0.78 SLC7A5 (0.54) SLC7A5ANPEPRNPEPDNPEPSLC1A3
Leucine SCHEMBL30527819 0.75 SLC7A5 (0.67) SLC7A5ANPEPRNPEPDNPEPSLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116675727-A Method for synthesizing amide and/or polypeptide by taking unprotected amino acid as ammonia component 广州医科大学 2023-09-01 CN disclosed
CN-116675726-A Method for synthesizing amide and/or polypeptide by using temporarily protected amino acid as ammonia component 广州医科大学 2023-09-01 CN disclosed
CN-110964085-B Preparation method of carfilzomib and derivatives thereof 扬子江药业集团有限公司 2023-07-07 CN disclosed