SCHEMBL29065857

SCHEMBL29065857

CCc1ccc(NC(c2cccc(Cl)c2)C2CCCCC2=O)cc1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.65
KDM4E B2RXH2 1/20 0.65
HPGD P15428 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
CA1 P00915 8/20 0.58
LMNA P02545 2/20 0.56
NPSR1 Q6W5P4 1/20 0.56
ADRB3 P13945 2/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30530167 1.00 MAPT (0.65) MAPTKDM4EHPGDSMN1; SMN2CA1
SCHEMBL30530130 0.89 MAPT (0.67) MAPTKDM4EHPGDSMN1; SMN2CA1
SCHEMBL29065884 0.89 MAPT (0.67) MAPTKDM4EHPGDSMN1; SMN2CA1
SCHEMBL30530168 0.88 MAPT (0.66) MAPTKDM4EHPGDSMN1; SMN2CA1
SCHEMBL29065868 0.88 MAPT (0.66) MAPTKDM4EHPGDSMN1; SMN2CA1
SCHEMBL30530190 0.88 CA1 (0.76) MAPTKDM4EHPGDSMN1; SMN2CA1
SCHEMBL29065861 0.88 CA1 (0.76) MAPTKDM4EHPGDSMN1; SMN2CA1
SCHEMBL30530157 0.87 CA1 (0.58) MAPTKDM4EHPGDSMN1; SMN2CA1
SCHEMBL30530181 0.86 CA1 (0.78) MAPTKDM4EHPGDSMN1; SMN2CA1
SCHEMBL29065858 0.80 MAPT (0.74) MAPTKDM4EHPGDSMN1; SMN2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116715596-A Method for synthesizing beta-aminoketone compound by synergistic catalysis of cyclopentadienyl titanium/Bronsted acid 宁夏师范学院 2023-09-08 CN disclosed