Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | STAT3 | P40763 | 1/20 | 0.62 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29066067 | 0.91 | ABCB1 (0.68) | ATMABCB1MAPTSMN1; SMN2TP53 | |
| SCHEMBL2218172 | 0.88 | ATM (0.64) | ATMSTAT3ABCB1MAPTSMN1; SMN2 | |
| SCHEMBL6349892 | 0.88 | ATM (0.68) | ATMSTAT3ABCB1MAPTSMN1; SMN2 | |
| SCHEMBL12435944 | 0.86 | ATM (0.59) | ATMSTAT3ABCB1MAPTSMN1; SMN2 | |
| SCHEMBL12436011 | 0.85 | ATM (0.64) | ATMSTAT3ABCB1MAPTSMN1; SMN2 | |
| SCHEMBL9616929 | 0.84 | AURKB (0.68) | AURKBMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8348359 | 0.84 | AURKB (0.64) | AURKBMAPTSMN1; SMN2TP53MEN1 | |
| SCHEMBL10904567 | 0.84 | AURKB (0.72) | AURKBMAPTSMN1; SMN2GAAMEN1 | |
| SCHEMBL16675161 | 0.83 | ABCB1 (0.68) | ATMABCB1MAPTSMN1; SMN2TP53 | |
| SCHEMBL16675167 | 0.83 | ABCB1 (0.68) | ATMABCB1MAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535304-B | Erianin analogue, and synthetic method and application thereof | 中国科学院成都生物研究所 | 2024-07-19 | — | — | CN | disclosed |
| CN-116535304-A | Erianin analogue, and synthetic method and application thereof | 中国科学院成都生物研究所 | 2023-08-04 | — | — | CN | disclosed |