Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 1/20 | 0.62 |
| ▸ | KRAS | P01116 | 1/20 | 0.62 |
| ▸ | CD274 | Q9NZQ7 | 18/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 9/20 | 0.43 |
| ▸ | PDCD1LG2 | Q9BQ51 | 9/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21207104 | 0.93 | HRAS (0.66) | HRASKRASCD274PDCD1PDCD1LG2 | |
| SCHEMBL30913765 | 0.93 | HRAS (0.66) | HRASKRASCD274PDCD1PDCD1LG2 | |
| SCHEMBL24329998 | 0.87 | HRAS (0.68) | HRASKRASCD274PDCD1PDCD1LG2 | |
| SCHEMBL29582873 | 0.87 | HRAS (0.68) | HRASKRASCD274PDCD1PDCD1LG2 | |
| SCHEMBL21201481 | 0.85 | HRAS (0.57) | HRASKRASCD274PDCD1PDCD1LG2 | |
| SCHEMBL21207018 | 0.84 | HRAS (0.58) | HRASKRASCD274PDCD1PDCD1LG2 | |
| SCHEMBL30222551 | 0.84 | HRAS (0.58) | HRASKRASCD274PDCD1PDCD1LG2 | |
| SCHEMBL21206993 | 0.83 | HRAS (0.59) | HRASKRASCD274PDCD1BRD4 | |
| SCHEMBL30222588 | 0.83 | HRAS (0.59) | HRASKRASCD274PDCD1BRD4 | |
| SCHEMBL30913745 | 0.81 | HRAS (0.54) | HRASKRASCD274PDCD1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116723839-A | Tricyclic heterobifunctional compounds for degrading target proteins | C4医药公司 | 2023-09-08 | — | — | CN | disclosed |