Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.69 |
| ▸ | PDE4A | P27815 | 4/20 | 0.69 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905822 | 0.88 | PDE4D (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL30084828 | 0.88 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL2889262 | 0.88 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL30084849 | 0.86 | PDE4D (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL2889923 | 0.86 | PDE4D (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL2888121 | 0.86 | PDE4B (0.72) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL29824457 | 0.86 | PDE4B (0.72) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL4163114 | 0.85 | PDE4B (0.77) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL7534706 | 0.84 | PDE4D (0.80) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL30084836 | 0.84 | PDE4D (0.80) | PDE4BPDE4DPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879884-B1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | RANBAXY LAB LTD (IN) | 2010-08-25 | — | — | EP | disclosed |
| EP-1879884-A1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117653-A1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |